John Dorian, J.D. (Zach Braff) to friends, is a boyishly handsome, self-deprecatingly funny, likeable guy who would be confident if he only realized his assets. Three years of medical school have prepared J.D. for his first day as an intern at Sacred Heart Hospital — but he has his doubts. As J.D. is thrown into the chaotic world of hospital life, we not only get to see the quirky characters that he encounters, but also hear the humorous commentary of thoughts streaming through J.D.’s head.By J.D.’s side is his best friend since college, the handsome and confident Chris Turk (Donald Faison). As a new surgical intern, Turk struts around with a gregarious and cocky demeanor that hides a terror that he only admits to J.D. Both guys initially have the hots for their attractive fellow intern, Elliot Reid (Sarah Chalke), but J.D. quickly finds out her beauty is only surpassed by a hyper competitive attitude.Guiding the interns education are those with more medical experience — which at this time is pretty much everyone. Dr. Robert Kelso (Ken Jenkins), Chief of Medicine, wants the interns to think they can count on him — until they actually need something. On the other side of the personality spectrum is Dr. Perry Cox (John C. McGinley), a steamroller of a man short on patience. However, beneath his gruff presence hides a truly good guy that J.D. learns to respect. Watching over the interns with a caustically teasing, but caring demeanor, is Nurse Carla Espinoza (Judy Reyes), a woman who is motherly and sexy at the same time.

Be as hip as John Dorian. Get yourself some scrubs, muss your hair and gel firmly in place, be a complete fool. Everyone will love you for being yourself.