Ben (Brendan Fraser) takes the news of his leukemia diagnosis pretty well. But it’s his sister Jordan (Christa Miller) who is having problems dealing with it. Also having a problem is J.D. (Zach Braff), who, unaccustomed to developing close friendships with patients, is not sure what to do. Remarkably, it is Dr. Cox (John C. McGinley) who is the voice of reason and compassion. That changes when Ben starts his chemotherapy treatments. Cox said he would stop by and visit, but he is nowhere to be seen. After he and J.D. have a talk, Cox puts aside his own fears and goes to see Ben. The chemotherapy treatments work better than expected and Ben goes into remission.

Meanwhile Turk (Donald Faison) and Elliot (Sarah Chalke) have their own issues to deal with. Turk is upset because he wasn’t chosen to assist on a difficult surgery. It’s a serious blow to his ego when he realizes that he isn’t the number one intern in the department - “smack your hand until it bleeds” Todd (Robert Maschio) is. Elliot is criticized during rounds by Dr. Kelso (Ken Jenkins) for the 100th time. But this time he gives her a chance to critique his work, anonymously. Instead of writing it herself, she has Carla (Judy Reyes) write the review to give it more of an impact. Carla writes a scathing attack on Dr. Kelso. But the joke is on Elliot when she finds out that no one else was asked to turn in an evaluation.